Reaction of hives to Levaquin

by Johanna
(Carson City, NV)

A few years ago, I was given a prescription for Levaquin by a dentist who said I had an infection in my mouth. I do not know why he did not just prescribe Amoxycillin. He gave me a sample pill before I left his office and I took it with a swig of water.


I went straight to Longs Drugs after that to fill the prescription. While I was waiting and browsing in the aisles, I noticed large bumps appearing on my arms. They were not itchy but were showing up with greater frequency all the time.

I went to the pharmacy desk and showed them my reaction, asking them what I should do. They told me to go and get some benadryl off the shelves, pay for it, and to take the recommended dosage. Fortunately, that did the trick. I had them call the dentist's office and they changed the prescription to amoxycillin, which did not give me any trouble.

I have never before or since had such a reaction to anything taken by mouth. Reading about some of the other reactions I could have had makes me shudder and realize that I was very lucky. I have made sure to note to any medical professionals that I am allergic to Levaquin so that I am not accidentally given one of this family of drugs.

Comments for Reaction of hives to Levaquin

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Simple Allergic Reaction
by: Kerri Knox, RN- The Immune Queen!

Hi Johanna,

You 'just' have a 'simple' allergic reaction, which is a common Side Effect of Levaquin and your reaction does NOT mean that you would have been affected with Levaquin Tendonitis or that you have a higher chance of being affected by it.

While you SHOULD always avoid the Quinolones, an allergic reaction is an ENTIRELY different reaction to these drugs than Levaquin Tendonitis. The people who have these disabling reactions, tendon ruptures, etc. are NOT allergic to them and do not get hives, etc. You are FORTUNATE to be allergic to these drugs because you will be unable to ever take them again. Yippee!

The people who experience Levaquin Tendonitis are not so lucky and have no outward signs that this reaction is happening until they have a ruptured tendon, panic attacks, disability, etc. And their reactions don't go away with Benadryl. The effects from Levaquin Tendonitis can last years or a lifetime...




Kerri Knox RN Immune Health Queen

Kerri Knox, RN- The Immune System Queen
Functional Medicine Practitioner
Immune System
Side Effects



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Extreme Case of Hives
by: Amy

I took one Levaquin pill (of a 7 day course) and immediately developed hives. I did not take another pill. I have had hives for 4 months on and off ever since. A few days ago, they were so severe that I ended up in the ER with tremendous hives all over by belly, legs, lip and throat. Has anyone else had a reaction like this that won't go away and apparently started by taking Levaquin?

Thank you, Kerri!
by: Johanna

Wow, I had no idea that Levaquin was so toxic and that I got off very lightly. I did think it strange to be prescribed with something other than Amoxycillin right off the bat, especially when I didn't even have an infection and it was a preventative measure.

Hives from Levaquin
by: Kenny

Just wanted to add that I too was given Levofloxacin (generic name for Levaquin) 500mg tablet and broke out in hives all over my body with much coverage. The hives were so big and spread out that I took photos to document them. I didn't find them extremely itchy, but I tried not to move around much either while I had them. I took Benedryl to calm them down, but that's all the effect it had on them. I still had them and they lasted about 4 days. I had to miss a few days of work due to them. They were even on my eyeball, inside my nose, roof of my mouth, gums, and private areas. This was in 2015. I have not had any recurrence of hives since then.

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